Reon -
The Science
So Reon contains caffeine and Vitamin B12. But what does that actually mean?

For many of us, caffeine is part of our daily ritual. It’s there when we need it, keeping our energy levels up, helping us stay alert, and improving our concentration levels.

Vitamin B12 occurs naturally in plants, animals and dairy and is known to reduce fatigue and tiredness.

But these aren’t the only reasons why these two remarkable ingredients have become so popular in modern foods and drinks.

Read on to find out what the latest research studies have to say about them.

  • Caffeine occurs in more than 60 different plants! It is found naturally in coffee, tea, chocolate, yerba mate, cola nuts,... (14)
  • Vitamin B12 is produced by microorganisms (neither plant nor animal!), also known as bacteria. The good type. (19)
  • Scientists and marketing people tend to drink the most coffee. Nurses and government professionals the least.
  • Caffeine increases dopamine levels, which create a positive state of mind, keeping you motivated and productive (6).
  • Caffeine has shown to improve long-term memory up to 24-hours after it has been taken (7)
  • Caffeine is thought to help you stay physically active for longer periods, letting you go #OnAndOn (9), (10).
  • Some 65% of studies show that caffeine causes significant improvements in team sports and power-based sports (11).
  • Caffeine is good for bees too. Recent studies have shown that caffeine can enhance their long-term memory!
  • Caffeine was first isolated from cocoa beans into its purest form, a white powder, in the 1820s by a German Scientist. (20)

  • The Dutch consume the most caffeine from coffee, tea and chocolate globally. On average 414 mg a day. (16)
  • Voltaire, the French philosopher, was said to have downed 50 cups of coffee a day.

If used in excess, caffeine can also have some negative effects, such as sleeplessness and dehydration. Always consume caffeine in moderate amounts and as part of a varied and healthy diet. Try the following to boost your energy naturally: (18)
  • Drink plenty of water. To fight symptoms of withdrawal and improve alertness.
  • Get a good night’s sleep. Boost your energy and combat fatigue naturally. (18)
  • Go for a brisk walk. Exercise when you’re tired will actually re-energise you. (21)
  • 1) Tse, W.S., et al., Caffeinated coffee enhances co-operative behavior in the Mixed Motive Game in healthy volunteers. Nutr Neurosci, 2009. 12(1): p. 21-7.
  • 2) Zwyghuizen-Doorenbos, A., et al., Effects of caffeine on alertness. Psychopharmacology, 1990. 100(1): p. 36-39.
  • 3) Smith, A.P., et al., Investigation of the Effects of Coffee on Alertness and Performance during the Day and Night. Neuropsychobiology, 1993. 27(4): p. 217-223.
  • 4) Maridakis, V., P.J. O'Connor, and P.D. Tomporowski, Sensitivity to change in cognitive performance and mood measures of energy and fatigue in response to morning caffeine alone or in combination with carbohydrate. Int J Neurosci, 2009. 119(8): p. 1239-58.
  • 5) Lorist, M.M., et al., Aging, Caffeine, and Information-Processing - an Event-Related Potential Analysis. Evoked Potentials-Electroencephalography and Clinical Neurophysiology, 1995. 96(5): p. 453-467.
  • 6) Solinas, M., et al., Caffeine Induces Dopamine and Glutamate Release in the Shell of the Nucleus Accumbens. The Journal of Neuroscience, 2002. 22(15): p. 6321-6324.
  • 7) Borota, D., et al., Post-study caffeine administration enhances memory consolidation in humans. Nat Neurosci, 2014. 17(2): p. 201-203.
  • 8) Ross, G.W. and H. Petrovitch, Current Evidence for Neuroprotective Effects of Nicotine and Caffeine Against Parkinson’s Disease. Drugs & Aging, 2001. 18(11): p. 797-806.
  • 9) Graham, T., Caffeine and Exercise. Sports Medicine, 2001. 31(11): p. 785-807.
  • 10) Goldstein, E.R., et al., International society of sports nutrition position stand: caffeine and performance. J Int Soc Sports Nutr, 2010. 7(1): p. 5.
  • 11) Astorino, T.A. and D.W. Roberson, Efficacy of Acute Caffeine Ingestion for Short-term High-Intensity Exercise Performance: A Systematic Review. The Journal of Strength & Conditioning Research, 2010. 24(1): p. 257-265.
  • 12) Nehlig, A. and G. Debry, Caffeine and sports activity: a review. Int J Sports Med, 1994. 15(5): p. 215-23.
  • 13) EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the safety of caffeine. EFSA Journal 2015;13(5):4102.
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